I am using the ToF fix 0.5.2.4.
The fix really got rid of a lot of stuttering issues for me when running in town areas and the mini-map.
However I do seem to get some sort of slowdown/drops during combat when multiple enemies are hit with an arte or when free-running. The fix interface stays around 60fps though. I did not had this without the mod/fix. I did use the settings as suggested in this image.
There is also a tab specific for tales of vesperia with enable depth of field, sharper shadows etc.
Can anyone give me some advice or such what to tinker with that might affect the battle performance? If unclear I can try make a video.